Aileen Ouyang, Ph.D.

Student

Biomedical Engineering

LinkedIn Profile

November 2015 - August 2016: M.S. Student

September 2016 - December 2020: Ph.D. Student

Research Interests:

Aileen's research focused on closed-loop neuromodulation for restoring autonomic organ functions in pre-clinical models.

pNEURO Lab Publications:

  1. Khurram A, Ross SE, Sperry ZJ, Ouyang A, Stephan CJ, Jiman AA, and Bruns TM. Chronic monitoring of lower urinary tract activity via a sacral dorsal root ganglia interface. Journal of Neural Engineering, 14: 036027, 2017.
  2. S.E. Ross*, Z. Ouyang*, S. Rajagopalan, T.M. Bruns. “Evaluation of decoding algorithms for estimating bladder pressure from dorsal root ganglia neural recordings,” Annals of Biomedical Engineering, 46(2): 233-246, 2018. *Co-first authors.
  3. Z. OuyangZ.J. Sperry, N. Barrera, T.M. Bruns. "Real-time bladder pressure estimation for closed-loop control in a detrusor overactivity model." IEEE Transactions on Neural Systems and Rehabilitation Engineering, DOI: 10.1109/TNSRE.2019.2912374, 2019.
  4. J.J. Xu, Z. Yousuf, Z. Ouyang, E. Kennedy, P. Lester, T. Martin, T. Bruns. “Urodynamic parameters and anesthetic depth vary depending on anesthetic agent (alfaxalone, dexmedetomidine, propofol) at doses necessary to facilitate preclinical testing.” Preprint at bioRxiv. DOI: 10.1101/868398.

pNEURO Lab Conference Proceedings:

  1. Ouyang Z, Barrera N, Marcu V, Socha A, Schwartz J, Sperry Z, Bruns TM. Behavioral Monitoring and Neuromodulation of Feline Voiding Function. Proceedings of 9th Intl IEEE EMBS Neural Engineering Conference, San Francisco, CA, March 20-23, 2019, 1058-1061. 
  2. Dongxiao Y, Jiman A, Ratze D, Huang S, Parizi S, Welle E, Ouyang Z, Patel P, Kushner M, Chestek C, Bruns TM, Yoon E, Seymour JP. Cuff-less, Penetrating Microneedle Array with Axon-Sized Dimensions for Peripheral Nerve Interfacing. Proceedings of 9th Intl IEEE EMBS Neural Engineering Conference, San Francisco, CA, March 20-23, 2019, 827-830.

pNEURO Lab Conference Abstracts:

  1. Ouyang A, Ross SE, Bruns TM. Decoding bladder activity with dorsal root ganglia neural signals using a Kalman filter. International Conference for Advanced Neurotechnology, Ann Arbor, MI, June 13-14, 2016.
  2. Ross SE, Khurram A, Ouyang A, Jiman AA, Sperry ZJ, Stephen CJ, Bruns TM. Chronic monitoring and excitation of lower urinary tract function. International Conference for Advanced Neurotechnology, Ann Arbor, MI, June 13-14, 2016.
  3. Ouyang A, Ross SE, Bruns TM. Decoding bladder activity with dorsal root ganglia neural signals using a Kalman filter. North American Neuromodulation Society – Neural Interfaces Conference Joint Meeting, Baltimore, MD, June 25-29, 2016.
  4. Ross SE, Khurram A, Ouyang A, Jiman AA, Sperry ZJ, Stephen CJ, Bruns TM. Chronic monitoring and excitation of lower urinary tract function. North American Neuromodulation Society – Neural Interfaces Conference Joint Meeting, Baltimore, MD, June 25-29, 2016.
  5. Ross SE, Khurram A, Sperry ZJ, Jiman AAA, Ouyang A, Zimmerman LL, Stephan CJ, Mahar CM, Rice IC, Bruns TM. Chronic spinal root interfacing for closed-loop control of the bladder. IEEE EMBS Annual Conference, Orlando, FL, August 16-20, 2016.
  6. Ouyang A, Ross SE, Bruns TM. Kalman filter decoding of bladder pressure from dorsal root ganglia activity. Society for Neuroscience 46 th Annual Meeting, San Diego, CA, November 12-16, 2016.
  7. Ross SE, Ouyang A, Khurram A, Jiman AA, Sperry ZJ, Stephen CJ, Bruns TM. Chronic monitoring and stimulation of the lower urinary tract during sedated and awake testing. Society for Neuroscience 46th Annual Meeting, San Diego, CA, November 12-16, 2016.
  8. Ouyang A, Bruns TM. Real-time estimation of bladder pressure through dorsal root ganglia recordings in an overactive bladder model. Society for Neuroscience 47th Annual Meeting, Washington D.C., November 11-15, 2017.
  9. Ouyang Z, Sperry ZJ, Barrera N, Bruns TM. Real-time estimation of bladder pressure through dorsal root ganglia recordings and closed-loop control in an overactive bladder feline model. Neural Interfaces Conference, Minneapolis, MN, June 25-27, 2018.
  10. Welle EJ, Patel PR, Jiman AA, Ouyang Z, Zimmerman L, Woods J, Seymour J, Bruns T, Weiland JD, Chestek CA. Characterization of carbon fiber recording tip exposure methods, coatings, and array durability. Neural Interfaces Conference, Minneapolis, MN, June 25-27, 2018.
  11. Ouyang Z, Barrera ND, Marcu VI, Schwartz JH, Socha AT, Sperry ZJ, Bruns TM. Behavioral monitoring and neuromodulation of feline bladder function. Society for Pelvic Research Annual Meeting, New Orleans, LA, December 1-2, 2018.
  12. Karam RA, Ouyang ZBruns TM, Majerus SJA, Damaser MS. Dynamic time warping parameter optimization for bladder event detection algorithm. Society for Pelvic Research Annual Meeting, New Orleans, LA, December 1-2, 2018.
  13. Yan D, Meli D, Jiman A, Ratze D, Kornexl M, Patel PR, Bottorff EC, Welle EJ, Ouyang Z, Ursu D, Parrish H, Kemp S, Chestek CA, Bruns TM, Yoon E, Seymour JP: A high-density tool for the autonomic nervous system: MIcroneedle Nerve Array (MINA) demonstrated in the rat cervical vagus nerve, International Society for Autonomic Neuroscience Congress 2019, Los Angeles, CA, 2019.
  14. Xu J, Yousef Z, Ouyang Z, Martin T, Lester P, Bruns T: Urodynamic and anesthetic parameters vary by anesthetic agent at doses necessary to facilitate urodynamic testing, American Association for Laboratory Animal Science National Meeting, Denver, CO, 2019.
  15. Jiman AA, Welle EJ, Patel PR, Bottorff EC, Ratze DC, Richie JM, Ouyang Z, Yan D, Zimmerman LL, Seymour JP, Chestek CA, Bruns TM: Monitoring of glucose- and insulin-triggered vagus nerve activity using carbon fiber microelectrode arrays in anesthetized rats, Society for Neuroscience Annual Meeting, Chicago, IL, 2019. 
  16. Ouyang Z, Barrera N, Sperry ZJ, Bottorff EC, Bruns TM: Real time closed loop control of bladder function with dorsal root ganglia sensory feedback and sacral root electrical stimulation, Society for Neuroscience Annual Meeting, Chicago, IL, 2019.   
  17. Xu JJ, Yousuf Z, Ouyang Z, Martin T, Lester PA, Bruns TM: Effects of sedative and anesthetic agents on urodynamic and anesthetic parameters in male cats, Fourth Annual Meeting of the Society for Pelvic Research, Charleston, SC, 2019. 
  18. Ouyang Z, Barrera N, Sperry ZJ, Bottorff EC, Bruns TM: Real time closed loop control of bladder function with dorsal root ganglia sensory feedback and sacral root electrical stimulation, Fourth Annual Meeting of the Society for Pelvic Research, Charleston, SC, 2019.   

Other pNEURO Lab Output:

  1. M. Levy, A. Khurram, S.E. Ross, Z.J. Sperry, A. Ouyang, A.A. Jiman, C.J. Stephan, T.M. Bruns, “Chronic monitoring of lower urinary tract activity via a sacral dorsal root ganglia interface,” Open Science Framework, 2017. http://dx.doi.org/10.17605/OSF.IO/WSBR6
  2. Z. Ouyang, S.E. Ross, T.M. Bruns. “Decoding algorithms and dorsal root ganglia neural recordings for estimating bladder pressure,” Open Science Framework, 2017. http://dx.doi.org/10.17605/OSF.IO/ZFYCH
  3. Z. Ouyang, T.M. Bruns, "Data for Behavioral Monitoring and Neuromodulation of Feline Voiding Function," Open Science Framework, 2018. https://osf.io/v96kg/
  4. Z. Ouyang, N. Barrera, Z. Sperry, T. Bruns. "Real-time estimation of bladder state in an overactive bladder model." Open Science Framework, 2019. https://osf.io/h6835/
  5. J.J. Xu, Z. Yousuf, Z. Ouyang, E. Kennedy, T. Martin, P. Lester, T. Bruns. “Urodynamic parameters and anesthetic depth vary depending on anesthetic agent (alfaxalone, dexmedetomidine, propofol) at doses necessary to facilitate preclinical testing.” Open Science Framework, 2019. https://osf.io/8zjkp/